Policosanol Monograph
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چکیده
Introduction Policosanol, an extract from sugar cane (Saccharum officinarum L.), has been heavily researched in Cuba in several human populations for its cholesterol-lowering properties. In addition to improving serum lipids, policosanol reduces LDL oxidation, decreases platelet aggregation, decreases smooth muscle proliferation, and improves symptoms of cardiovascular disease. Side effects are virtually non-existent.
منابع مشابه
Effects of policosanol on gastroprotective action of D-002
Introduction: policosanol, a mixture of higher aliphatic alcohols purified from sugar cane wax, is used to treat hypercholesterolemia. D-002 (Abexol), a mixture of higher aliphatic alcohols from beeswax, is an antioxidant supplement with gastroprotective effects. Then, concomitant intake of D-002 and policosanol may occur in routine practice, so potential pharmacological interactions between th...
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Policosanol is a cholesterol-lowering drug well tolerated in different populations, including those with high consumption of concomitant drugs, and the frequency of adverse events (AE) has been very low, suggesting a low risk of adverse drug interactions. Benzodiazepines (BZPs) are widely consumed to manage anxiety and sleep disorders in the elderly. Drug to drug interactions (DDI) with BZP are...
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Policosanol is a mixture of higher aliphatic alcohols purified from sugar cane wax, with cholesterol-lowering effects demonstrable in experimental models and in patients with type II hypercholesterolemia. The protective effects of policosanol on atherosclerotic lesions experimentally induced by lipofundin in rabbits and rats and spontaneously developed in stumptail monkeys have been described. ...
متن کاملPhotostability studies of retinyl palmitate entrapped in policosanol oleogel matrices
............................................................................................................................ xi CHAPTER 1. GENERAL INTRODUCTION ......................................................................... 1 Thesis Organization ............................................................................................................. 1 Literature Review ..............
متن کاملEffect of policosanol on the hepatic cholesterol biosynthesis of normocholesterolemic rats.
We have suggested previously, measuring 14C-acetate incorporation into free cholesterol, that oral administration of policosanol inhibits hepatic cholesterol biosynthesis in rats. Nevertheless, since acetate has limitations to study cholesterol synthesis in vivo, we now investigate rates of incorporation of labeled water into hepatic sterol after policosanol treatment. Absolute rates of incorpo...
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تاریخ انتشار 2004